职称:副教授

电子邮箱:jiszhang@tsinghua.edu.cn

电话:010-62773017

地址:北京清华大学工物馆572 化学工程联合国家重点实验室

邮编:100084

个人简介

分别于2009年、2014年在清华大学化学工程系获得学士和博士学位。2014-2015年在清华大学化学工程系做博后,2015-2017年在麻省理工学院化工系做博后,2017年起在清华大学化学工程系从事教学和科研工作,2020年晋升副教授。主讲《化工设计》(本科生)和《化学品的智能制造》(本科生)课程。

研究方向

1. 微填充床用于加氢、氧化等

针对医药中间体和精细化工等行业,基于微填充床技术,研究微填充床内气液流动、传质和反应过程,研究新型填充材料和催化剂负载新技术,开发基于微填充床技术的新工艺和新设备。

2. 流动化学在医药中间体生产中的应用

面向原料药合成行业,针对加氢、臭氧化、偶联反应和傅克烷基化等典型过程,开发绿色的连续合成新技术,开发新型智能全自动化学合成系统。

3. 基于微器件的在线表征和分析技术

面向化学、化工和生物等领域,基于微器件混合高效、传质传热效率高、物料消耗少和安全可靠等特点,开发基于微反应器和微器件的在线表征和分析技术,比如在线测定反应热和反应动力学,快速测定气/液体系的溶解度、扩散系数和反应动力学,无细胞蛋白质合成,测定酶催化动力学等。

承担课题

1. 国家自然科学基金委员会,重大项目(项目骨干),21991103,高含能和高活性化学品制备的微化工过程和 科学基础,2020.01-2024.12

2. 国家自然科学基金面上项目21978146,微填充床反应器内气液两相流动和传质性能强化基础研究,2020.1- 2023.12

3. 国家自然科学基金优秀青年基金项目22022809,微反应器技术与过程强化,2021.1- 2023.12

4. 清华大学工科青年专项 20197050015,微填充床反应器内药物分子连续加氢反应研究,2019.8-2020.12

5. 国家自然科学基金青年基金项目 21506110,有机催化体系内贝克曼重排反应的微型化研究 2016.1- 2018.12

6. 博士后科学基金面上资助,2015M570111,微反应器内有机酸催化的环己酮肟贝克曼重排反应研究

7. 横向课题和技术转化多项

学术论文

2022

1. Duan, X.; Yin, J.; Huang, M.; Wang, P.; Zhang, J. Hydrogenation Kinetics of Halogenated Nitroaromatics over Pt/C in a Continuous Micro-Packed Bed Reactor. Chemical Engineering Science 2022, 251, 117483.

2. Zhang, C.; Duan, X.; Yin, J.; Lou, F.; Zhang, J. Copper/TEMPO-Catalyzed Continuous Aerobic Alcohol Oxidation in a Micro-Packed Bed Reactor. Reaction Chemistry & Engineering 2022, 7 (6), 1289–1296.

3. Ma, C.; Huang, M.; Yin, J.; Lou, F.; Zhang, J. Investigation of Hydrogenation and Mass Transfer Performance in Micropacked Beds with Highly Active Monolithic Catalysts. Chemical Engineering Science 2022, 251, 117477.

4. Chen, J.; Zhou, C.; Xie, B.; Zhang, J. Simulation of the Enhancement of Dean Flow on the Liquid–Liquid Extraction in Membrane Contactors. Separation and Purification Technology 2022, 285, 120384.

5. Duan, X.; Yin, J.; Feng, A.; Huang, M.; Fu, W.; Xu, W.; Huang, Z.; Zhang, J. Continuous Hydrogenation of Halogenated Nitroaromatic Compounds in a Micropacked Bed Reactor. J Flow Chem 2022, 12 (1), 121–129.

6. Duan, X.; Yin, J.; Huang, M.; Feng, A.; Fu, W.; Chen, H.; Huang, Z.; Ding, Y.; Zhang, J. Hydrogenation Kinetics of M-Dinitrobenzene in a Continuous Micro-Packed Bed Reactor. Chemical Engineering Science 2022, 248, 117113.

7. Liang, R.; Duan, X.; Zhang, J.; Yuan, Z. Bayesian Based Reaction Optimization for Complex Continuous Gas–Liquid–Solid Reactions. Reaction Chemistry & Engineering 2022, 7 (3), 590–598.

2021

1. Cao, Q.; Sang, L.; Tu, J.; Xiao, Y.; Liu, N.; Wu, L.; Zhang, J. Rapid Degradation of Refractory Organic Pollutants by Continuous Ozonation in a Micro-Packed Bed Reactor. Chemosphere 2021, 270, 128621.

2. Xie, B.; Zhou, C.; Sang, L.; Ma, X.; Zhang, J. Preparation and Characterization of Microbubbles with a Porous Ceramic Membrane. Chemical Engineering and Processing - Process Intensification 2021, 159, 108213.

3. Xie, B.; Zhou, C.; Huang, X.; Chen, J.; Ma, X.; Zhang, J. Microbubble Generation in Organic Solvents by Porous Membranes with Different Membrane Wettabilities. Ind. Eng. Chem. Res. 2021, 60 (23), 8579–8587.

4. Ma, C.; Sang, L.; Duan, X.; Yin, J.; Zhang, J. An Efficient Method for Enhancing Adhesion and Uniformity of Al2O3 Coatings on Nickel Micro-Foam Used in Micropacked Beds. Chinese Journal of Chemical Engineering 2021, 39, 162–172.

5. Zhou, C.; Xie, B.; Chen, J.; Fan, Y.; Zhang, J. Enhancement of Gas-Liquid Mass Transfer in Curved Membrane Contactors with the Generation of Dean Vortices. Journal of Membrane Science 2021, 636, 119592.

6. Cao, Q.; Lou, F.; Liu, N.; Zhang, J.; Wu, L. Continuous Catalytic Ozonation of Antibiotics Using Mn and Cu Oxides on γ-Al2O3 Pellets in a Micropacked Bed Reactor. ACS EST Water 2021, 1 (8), 1911–1920.

7. Duan, X.; Wang, X.; Chen, X.; Zhang, J. Continuous and Selective Hydrogenation of Heterocyclic Nitroaromatics in a Micropacked Bed Reactor. Org. Process Res. Dev. 2021, 25 (9), 2100–2109.

8. Ma, C.; Duan, X.; Yin, J.-B.; Sang, L.; Zhang, J. Preparation of Pd/Al2O3/Nickel Microfoam Catalysts by Electrodeposition for Hydrogenation in a Micropacked Bed Reactor. Ind. Eng. Chem. Res. 2021, 60 (45), 16522–16532.

2020

1. Sang, L.; Feng, X.; Tu, J.; Xie, B.; Luo, G.; Zhang, J. Investigation of External Mass Transfer in Micropacked Bed Reactors. Chemical Engineering Journal 2020, 393, 124793.

2. Zhang, C.; Zhang, J.; Luo, G. Kinetics Determination of Fast Exothermic Reactions with Infrared Thermography in a Microreactor. J Flow Chem 2020, 10 (1), 219–226.

3. Lin, X.; Zhou, C.; Zhu, S.; Deng, H.; Zhang, J.; Lu, Y. O2-Tuned Protein Synthesis Machinery in Escherichia Coli-Based Cell-Free System. Frontiers in Bioengineering and Biotechnology 2020, 8.

4. Duan, X.; Tu, J.; R. Teixeira, A.; Sang, L.; F. Jensen, K.; Zhang, J. An Automated Flow Platform for Accurate Determination of Gas–Liquid–Solid Reaction Kinetics. Reaction Chemistry & Engineering 2020, 5 (9), 1751–1758.

5. Zhou, C.; Xie, B.; Li, S.; Zhang, J. Rapid Measurement of Gas Diffusivity in Liquids Using a Tube-in-Tube Reactor with an Unsteady-State Strategy. AIChE Journal 2020, 66 (11), e17015.

6. Tu, J.; Sang, L.; Cheng, H.; Ai, N.; Zhang, J. Continuous Hydrogenolysis of N-Diphenylmethyl Groups in a Micropacked-Bed Reactor. Org. Process Res. Dev. 2020, 24 (1), 59–66.

7. Zhou, C.; Lin, X.; Lu, Y.; Zhang, J. Flexible On-Demand Cell-Free Protein Synthesis Platform Based on a Tube-in-Tube Reactor. React. Chem. Eng. 2020, 5 (2), 270–277.

8. Sang, L.; Tu, J.; Cheng, H.; Luo, G.; Zhang, J. Hydrodynamics and Mass Transfer of Gas–Liquid Flow in Micropacked Bed Reactors with Metal Foam Packing. AIChE Journal 2020, 66 (2), e16803.

9. Du, C.; Wang, P.; Hu, Y.; Zhang, J.; Luo, G. Liquid–Liquid Mass Transfer Enhancement in Milliscale Packed Beds. Ind. Eng. Chem. Res. 2020, 59 (9), 4048–4057.

10. Zhang, H.; Kopfmüller, T.; Achermann, R.; Zhang, J.; Teixeira, A.; Shen, Y.; Jensen, K. F. Accessing Multidimensional Mixing via 3D Printing and Showerhead Micromixer Design. AIChE Journal 2020, 66 (4), e16873.

2019

1. Lan, M.; Zhao, Z.; Zeng, Q.; Zhou, C.; Zhang, J. Rapid Measurement of Gas Solubility in Ionic Liquids with a Simple Tube-in-Tube Reactor. Ind. Eng. Chem. Res. 2019, 58 (16), 6696–6703.

2. Zhang, J.; Teixeira, A. R.; Zhang, H.; Jensen, K. F. Flow Toolkit for Measuring Gas Diffusivity in Liquids. Anal. Chem. 2019, 91 (6), 4004–4009.

3. Du, C.; Zhang, J.; Li, L.; Wang, K.; Luo, G. A Modified Mixed-Acid Catalytic System for Beckmann Rearrangement of Cyclohexanone Oxime. AIChE Journal 2019, 65 (6), e16603.

4. Deng, J.; Zhang, J.; Wang, K.; Luo, G. Microreaction Technology for Synthetic Chemistry. Chinese Journal of Chemistry 2019, 37 (2), 161–170.

5. Du, C.; Hu, Y.; Zhang, J.; Luo, G. Ultra-Low Formation of Octahydrophenazine in the Beckmann Rearrangement of Cyclohexanone Oxime Using a Microreactor. React. Chem. Eng. 2019, 4 (11), 1991–1999.

6. Li, L.; Zhang, J.; Du, C.; Luo, G. Intensification of the Sulfuric Acid Alkylation Process with Trifluoroacetic Acid. AIChE Journal 2019, 65 (1), 113–119.

2018

1. Zhang, J.; Teixeira, A. R.; Jensen, K. F. Automated Measurements of Gas-Liquid Mass Transfer in Micropacked Bed Reactors. AIChE Journal 2018, 64 (2), 564–570.

2. Du, C.; Zhang, J.; Luo, G. Organocatalyzed Beckmann Rearrangement of Cyclohexanone Oxime in a Microreactor: Kinetic Model and Product Inhibition. AIChE Journal 2018, 64 (2), 571–577.

3. Navarro-Brull, F. J.; Teixeira, A. R.; Zhang, J.; Gómez, R.; Jensen, K. F. Reduction of Dispersion in Ultrasonically-Enhanced Micropacked Beds. Ind. Eng. Chem. Res. 2018, 57 (1), 122–128.

4. Navarro-Brull, F. J.; Teixeira, A. R.; Zhang, J.; Gómez, R.; Jensen, K. F. Reduction of Dispersion in Ultrasonically-Enhanced Micropacked Beds. Ind. Eng. Chem. Res. 2018, 57 (1), 122–128.

2017

1. Zhang, J.; Teixeira, A. R.; Zhang, H.; Jensen, K. F. Automated in Situ Measurement of Gas Solubility in Liquids with a Simple Tube-in-Tube Reactor. Anal. Chem. 2017, 89 (16), 8524–8530.

2. Du, C.; Zhang, J.; Li, L.; Wang, K.; Luo, G. Impurity Formation in the Beckmann Rearrangement of Cyclohexanone Oxime to Yield ε-Caprolactam. Ind. Eng. Chem. Res. 2017, 56 (48), 14207–14213.

3. Zhang, J.; Wang, K.; Teixeira, A. R.; Jensen, K. F.; Luo, G. Design and Scaling Up of Microchemical Systems: A Review. Annual Review of Chemical and Biomolecular Engineering 2017, 8 (1), 285–305.

4. Lin, X.; Yan, S.; Zhou, B.; Wang, K.; Zhang, J.; Luo, G. Highly Efficient Synthesis of Polyvinyl Butyral (PVB) Using a Membrane Dispersion Microreactor System and Recycling Reaction Technology. Green Chem. 2017, 19 (9), 2155–2163.

2016

1. Zhang, J.; Wang, K.; Zhang, C.; Luo, G. Safety Evaluating of Beckmann Rearrangement of Cyclohexanone Oxime in Microreactors Using Inherently Safer Design Concept. Chemical Engineering and Processing: Process Intensification 2016, 110, 44–51.

2. Zhang, J.; Zhang, C.; Liu, G.; Luo, G. Measuring Enthalpy of Fast Exothermal Reaction with Infrared Thermography in a Microreactor. Chemical Engineering Journal 2016, 295, 384–390.

3. Zhang, C.; Zhang, J.; Luo, G. Kinetic Study and Intensification of Acetyl Guaiacol Nitration with Nitric Acid—Acetic Acid System in a Microreactor. Journal of Flow Chemistry 2016, 6 (4), 309–314.

4. Wang, P.; Zhang, J.; Wang, K.; Luo, G.; Xie, P. Kinetic Study of Reactions of Aniline and Benzoyl Chloride Using NH3 as Acid Absorbent in a Microstructured Chemical System. Ind. Eng. Chem. Res. 2016, 55 (22), 6310–6316.

5. Lin, X.; Zhang, J.; Wang, K.; Luo, G. Determination of the Micromixing Scale in a Microdevice by Numerical Simulation and Experiments. Chemical Engineering & Technology 2016, 39 (5), 909–917.

6. Li, L.; Zhang, J.; Wang, K.; Xu, J.; Luo, G. Droplet Formation of H2SO4/Alkane System in a T-Junction Microchannel: Gravity Effect. AIChE Journal 2016, 62 (12), 4564–4573.

7. Li, L.; Zhang, J.; Shen, C.; Wang, Y.; Luo, G. Oxidative Desulfurization of Model Fuels with Pure Nano-TiO2 as Catalyst Directly without UV Irradiation. Fuel 2016, 167, 9–16.

2015

1. Zhang, J.; Dong, C.; Du, C.; Luo, G. Organocatalyzed Beckmann Rearrangement of Cyclohexanone Oxime in a Microchemical System. Org. Process Res. Dev. 2015, 19 (2), 352–356.

2. Wang, P.; Wang, K.; Zhang, J.; Luo, G. Preparation of Poly( p -Phenylene Terephthalamide) in a Microstructured Chemical System. RSC Advances 2015, 5 (79), 64055–64064.

3. Wang, P.; Wang, K.; Zhang, J.; Luo, G. Non-Aqueous Suspension Polycondensation in NMP-CaCl2/Paraffin System — A New Approach for the Preparation of Poly(p-Phenylene Terephthalamide). Chin J Polym Sci 2015, 33 (4), 564–575.

4. Wang, P.; Wang, K.; Zhang, J.; Luo, G. Kinetic Study of Reactions of Aniline and Benzoyl Chloride in a Microstructured Chemical System. AIChE Journal 2015, 61 (11), 3804–3811.

5. Wang, K.; Zhang, J.; Zheng, C.; Dong, C.; Lu, Y.; Luo, G. A Consecutive Microreactor System for the Synthesis of Caprolactam with High Selectivity. AIChE Journal 2015, 61 (6), 1959–1967.

6. Lu, Y.; Xin, D.; Zhang, J.; Luo, G. Modeling Ethyl Diazoacetate Synthesis in an Adiabatic Microchemical System. Chemical Engineering Journal 2015, 273, 406–412.

7. Lu, Y.; Wang, R.; Zhang, J.; Jin, Q.; Luo, G. Evaluation of an Improved Epichlorohydrin Synthesis from Dichloropropanol Using a Microchemical System. Chinese Journal of Chemical Engineering 2015, 23 (7), 1123–1130.

8. Lin, X.; Wang, K.; Zhang, J.; Luo, G. Process Intensification of the Synthesis of Poly(Vinyl Butyral) Using a Microstructured Chemical System. Ind. Eng. Chem. Res. 2015, 54 (14), 3582–3588.

9. Lin, X.; Wang, K.; Zhang, J.; Luo, G. Liquid–Liquid Mixing Enhancement Rules by Microbubbles in Three Typical Micro-Mixers. Chemical Engineering Science 2015, 127, 60–71.

10. Dong, C.; Wang, K.; Zhang, J.; Luo, G. Reaction Kinetics of Cyclohexanone Ammoximation over TS-1 Catalyst in a Microreactor. Chemical Engineering Science 2015, 126, 633–640.

2014&Before

1. Zhang, J.; Wang, K.; Lin, X.; Lu, Y.; Luo, G. Intensification of Fast Exothermic Reaction by Gas Agitation in a Microchemical System. AIChE Journal 2014, 60 (7), 2724–2730.

2. Zhang, J.; Riaud, A.; Wang, K.; Lu, Y.; Luo, G. Beckmann Rearrangement of Cyclohexanone Oxime to ε-Caprolactam in a Modified Catalytic System of Trifluoroacetic Acid. Catal Lett 2014, 144 (1), 151–157.

3. Dong, C.; Zhang, J.; Wang, K.; Luo, G. Micromixing Performance of Nanoparticle Suspensions in a Micro-Sieve Dispersion Reactor. Chemical Engineering Journal 2014, 253, 8–15.

4. Zhang, J.; Lu, Y.; Wang, K.; Luo, G. Novel One-Step Synthesis Process from Cyclohexanone to Caprolactam in Trifluoroacetic Acid. Ind. Eng. Chem. Res. 2013, 52 (19), 6377–6381.

5. Zhang, J.; Wang, K.; Lu, Y.; Luo, G. Beckmann Rearrangement of Cyclohexanone Oxime in a Microchemical System: The Role of SO3 and Product Inhibition. AIChE Journal 2012, 58 (10), 3156–3160.

6. Zhang, J.; Wang, K.; Lu, Y.; Luo, G. Beckmann Rearrangement in a Microstructured Chemical System for the Preparation of ε-Caprolactam. AIChE Journal 2012, 58 (3), 925–931.

7. Zhang, J.; Lu, Y.; Jin, Q.; Wang, K.; Luo, G. Determination of Kinetic Parameters of Dehydrochlorination of Dichloropropanol in a Microreactor. Chemical Engineering Journal 2012, 203, 142–147.

8. Zhang, J.; Tan, J.; Wang, K.; Lu, Y.; Luo, G. Chlorohydrination of Allyl Chloride to Dichloropropanol in a Microchemical System. Ind. Eng. Chem. Res. 2012, 51 (45), 14685–14691.

9. Tan, J.; Zhang, J.; Lu, Y.; Xu, J.; Luo, G. Process Intensification of Catalytic Hydrogenation of Ethylanthraquinone with Gas-Liquid Microdispersion. AIChE Journal 2012, 58 (5), 1326–1335.

10. Zhang, J.; Wang, K.; Lu, Y.; Luo, G. Characterization and Modeling of Micromixing Performance in Micropore Dispersion Reactors. Chemical Engineering and Processing: Process Intensification 2010, 49 (7), 740–747.

荣誉奖励

1. 国家自然科学基金 优秀青年基金

2. Journal of Flow Chemistry “Emerging Investigators”,2019

3. Ind. & Eng. Chem. Res “Influential Researchers”,2019

4. 清华大学优秀博士论文,2014

5. 北京市优秀毕业生,2014

6. 北京高校优秀辅导员,2014

7. 教育部博士研究生学术新人奖,2012

8. 清华大学优秀毕业生,北京市三好学生,2009

在读学生

段笑南(2019级博士)

章承浩(2020级博士)

张家昊(2021级博士)

谢冰琪(2022级博士)

范以薇(2022级博士)

陈俊新(2020级硕士)

彭子频(2020级联合培养硕士)

段炼(2020级联合培养硕士)

已毕业学生

博士(毕业时间)

周才金(2022)

本科(毕业课题时间):

蓝敏乐(2018),曾庆秋霖(2018),朱云帆(2021),范以薇(2022)

访问学生

屠佳成,2018-2020

曹强, 2019-2021

黄小婷,2019-2021

娄锋炎,2020-2022